Patterns of respiratory pathogen circulation in rural coastal Kenya

Munywoki PK, Koech DC, Agoti CN, Cane PA, Medley GF, Nokes DJ. Continuous Invasion by Respiratory Viruses Observed in Rural Households During a Respiratory Syncytial Virus Seasonal Outbreak in Coastal Kenya. Clin Infect Dis. 2018 Oct 30;67(10):1559-1567. doi: 10.1093/cid/ciy313.


A household-based active surveillance during RSV season was conducted in 47 households in Kilifi Kenya. This study showed that 93.4% of the study participants had at least 1 virus detected. Adenovirus (AdV), human coronavirus (HCoV) and rhinovirus (RV) were the most prevalent during the RSV season. The individual attack rates declined with increasing age for most pathogens. Coinfection detection was common (13.4%-17.4%) and was higher among the symptomatic cases. The prevalence of RSV (and HMPV, PIV3 and RV) were higher among the hospital cases than in the community. Therefore, the frequency distribution of viruses could differ between community and hospital settings. Studies with a longer surveillance (particularly with multiple years) and studies investigating a wider range of respiratory viruses would provide more comprehensive data on virus circulation and year-to-year variation.

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