Immunological and Inflammatory Biomarkers of susceptibility and severity in Adult RSV Infections.

Dexter J Wiseman, Ryan S Thwaites, Simon B Drysdale, Sophie Janet, Gavin C Donaldson, Jadwiga A Wedzicha, Peter J Openshaw, the RESCEU Investigators.


Respiratory syncytial virus (RSV) is the most common cause of bronchiolitis in young infants. However, it is also a significant pathogen in older adults. Validated biomarkers of RSV disease severity would benefit diagnostics, treatment decisions, and prophylactic interventions. This review summarizes knowledge of biomarkers for RSV disease in adults.

A literature review was performed using Ovid Medline, Embase, Global health, Scopus, and Web of Science for articles published 1946–October 2016. Nine articles were identified plus 9 from other sources.

Full article here.