Deniz Öner, Simon B Drysdale, Calum McPherson, Gu-Lung Lin, Sophie Janet, Jonathan Broad, Andrew J Pollard, Jeroen Aerssens, RESCEU Investigators
Abstract
Background
Clinical manifestations of respiratory syncytial virus (RSV) infection vary widely from mild, self-limiting illness to severe life-threatening disease. There are gaps in knowledge of biomarkers to objectively define severe disease and predict clinical outcomes.
Methods
A systematic search was performed, 1945–March 2019 in databases Ovid Medline, Embase, Global health, Scopus, and Web of Science. Risk of bias was assessed using the Cochrane tool.
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