Biomarkers for disease severity in children infected with respiratory syncytial virus (RSV): a systematic literature review

Deniz Öner, Simon B Drysdale, Calum McPherson, Gu-Lung Lin, Sophie Janet, Jonathan Broad, Andrew J Pollard, Jeroen Aerssens, RESCEU Investigators

Clinical manifestations of respiratory syncytial virus (RSV) infection vary widely from mild, self-limiting illness to severe life-threatening disease. There are gaps in knowledge of biomarkers to objectively define severe disease and predict clinical outcomes.

A systematic search was performed, 1945–March 2019 in databases Ovid Medline, Embase, Global health, Scopus, and Web of Science. Risk of bias was assessed using the Cochrane tool.

Full article here.